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Effects of High-Intensity Functional Training on mir143, GLUT4 Expression, Insulin Resistance, and Total Antioxidant Capacity in Overweight Male Military Personnel
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Hamdollah Hadi *   |
| Physical Education and Sport Science Department, Police University, Tehran, Iran , amir.hadi1@gmail.com |
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Abstract: (859 Views) |
Background and Aim: Obesity and overweight represent major risk factors for mortality and chronic diseases. This study investigated the effects of high-intensity functional training (HIFT) on mir143 expression, GLUT4 levels, insulin resistance, and total antioxidant capacity in overweight military personnel.
Methods: Forty healthy overweight male military personnel were randomly assigned to either an 8-week HIFT program (3 sessions/week) or a control group. Fasting blood samples were collected pre- and post-intervention to measure mir143, GLUT4, insulin resistance (HOMA-IR), and total antioxidant capacity (TAC).
Results: The levels of mir143 and insulin resistance showed a significant decrease in the functional training group compared to the control group. Additionally, GLUT4 levels and TAC demonstrated a significant increase in the functional training group versus the control group.
Conclusion: These results provide compelling evidence for the beneficial effects of high-intensity functional training on mir143, GLUT4, insulin resistance, and TAC in overweight men. However, further studies are deemed necessary. |
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| Keywords: Functional training, Overweight, mir143, GLUT4, Insulin resistance, Total antioxidant capacity |
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Full-Text [PDF 602 kb]
(381 Downloads)
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Type of Study: Original Article |
Subject:
Marine Medicine
Received: 2024/08/20 | Accepted: 2025/06/3 | Published: 2025/06/20
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