Medical and educational care and the creation of special measures to prevent the spread of the disease are of great importance in maintaining the health of seafarers. Direct and immediate access to appropriate medical care always is not available to this group. Given that sailing is a dangerous occupation with a higher mortality rate than many onshore jobs, self-care is the most common behavioral response to prevent common diseases in this group. The most important achievement of strengthening the self-care approach is that sailors make the right decisions about the proper use of health care and choose and implement appropriate self-care behaviors for health problems. Sailors' self-care can include prevention of occupational diseases, prevention and protection of occupational and mechanical detrimental factors, prevention of ergonomic detrimental factors, prevention of chemical detrimental factors, prevention of physical detrimental factors, prevention of nutritional problems. Self-care in seafarers clearly increases the efficiency and individual skills of sailors against disease. On the other hand, learning self-care activities can lead sailors to stay healthy, increase a person's adaptation to the environment and health problems, increase the ability of sailors to take care of themselves, and reduce the incidence of disability and treatment costs.